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ŚB 11.21.1

श्रीभगवानुवाच
य एतान् मत्पथो हित्वा भक्तिज्ञानक्रियात्मकान् ।
क्षुद्रान् कामांश्चलै: प्राणैर्जुषन्त: संसरन्ति ते ॥ १ ॥
śrī-bhagavān uvāca
ya etān mat-patho hitvā
bhakti-jñāna-kriyātmakān
kṣudrān kāmāṁś calaiḥ prāṇair
juṣantaḥ saṁsaranti te

Synonyms

śrī-bhagavān uvācathe Supreme Personality of Godhead said; yethose who; etānthese; mat-pathaḥmeans for achieving Me; hitvāgiving up; bhaktidevotional service; jñānaanalytic philosophy; kriyāregulated work; ātmakānconsisting of; kṣudrāninsignificant; kāmānsense gratification; calaiḥby the flickering; prāṇaiḥsenses; juṣantaḥcultivating; saṁsarantiundergo material existence; tethey.

Translation

The Supreme Personality of Godhead said: Those who give up these methods for achieving Me, which consist of devotional service, analytic philosophy and regulated execution of prescribed duties, and instead, being moved by the material senses, cultivate insignificant sense gratification, certainly undergo the continual cycle of material existence.

Purport

As clearly explained by Lord Kṛṣṇa in the previous chapters, philosophical analysis and also the performance of prescribed duties are ultimately meant for achieving Kṛṣṇa consciousness, or pure love of God. Devotional service, based on hearing and chanting the glories of the Lord, directly engages the conditioned soul in the Lord’s loving service and thus is the most efficient means of achieving the Lord. All three processes, however, share a common goal, Kṛṣṇa consciousness. Now the Lord describes those who, being completely absorbed in material sense gratification, do not adopt any authorized means to achieve the Lord’s mercy. Currently, hundreds of millions of unfortunate human beings fit squarely into this category and, as described here, perpetually suffer the bondage of material existence.