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ŚB 12.4.6

एष प्राकृतिको राजन् प्रलयो यत्र लीयते ।
अण्डकोषस्तु सङ्घातो विघाट उपसादिते ॥ ६ ॥
eṣa prākṛtiko rājan
pralayo yatra līyate
aṇḍa-koṣas tu saṅghāto
vighāta upasādite

Synonyms

eṣaḥthis; prākṛtikaḥof the elements of material nature; rājanO King Parīkṣit; pralayaḥthe annihilation; yatrain which; līyateis dissolved; aṇḍa-koṣaḥthe egg of the universe; tuand; saṅghātaḥthe amalgamation; vighātethe cause of its disruption; upasāditebeing encountered.

Translation

O King, upon the annihilation of the material elements, the universal egg, comprising the elemental amalgamation of creation, is confronted with destruction.

Purport

It is significant that Śukadeva Gosvāmī, the spiritual master of King Parīkṣit, is broadly discussing cosmic annihilation just before the death of his disciple. By attentively hearing the story of universal destruction, one can easily understand one’s personal departure from this temporary world to be an insignificant incident within the gigantic scope of the total material manifestation. By his deep and relevant discussions of the creation of God, Śukadeva Gosvāmī, as an ideal spiritual master, is preparing his disciple for the moment of death.